产品名称：大黄素

英文名称：Emodin

CAS号 518-82-1

分子式 C15H10O5

分子量270.24

属性
溶解性 Soluble in ethanol, sodium carbonate solution, DMSO (1 mg/ml), aqueous alkali, 1eq. NaOH (100 mM), ammonium hydroxide (10 mg/ml), ether, chloroform, benzene , and THF. Insoluble in water.
敏感性 Light,Air sensitive
存贮条件 储存温度 2-8°C
熔点 256-257°C
密度 1.5830
描述
别名 朱砂莲甲素;1,3,8-三羟基-6-甲基蒽醌;2-甲基-4,5,7-三羟基蒽醌;6-甲基-1,3,8-三羟基蒽醌;;1,3,8-Tri-hydroxy-6-methyl-anthra-quinone 6-Methyl-1,3,8-tri-hydroxy-anthra-quinone Emodol Frangula-emodin
产品介绍 溶于乙醇，略溶于乙醚、氯仿、苯，不溶于水。溶于苛性碱水溶液、碳本酸钠水溶液，氨溶液中显樱红色。
用途 抑制NF -κB活化及粘附分子的表达。酪蛋白激酶2（CK2的）抑制剂.
生化机理 Emodin is a potent Lck (p56lck tyrosine kinase) inhibitor (IC50 = 18.5 μM). Selectively blocks the growth of v-ras transformed human bronchial epithelial cells (IC50 = 15 μM). Emodin has been shown to suppress HER2/neu tyrosine kinase activity in HER2/neu overexpressing breast cancer cells. Emodin is an inhibitor of Casein Kinase.
包装 E106692-1g,E106692-100mg,E106692-500mg in glass bottle